Inspired by the true story of former Sheriff Ralph Lamb, Vegas follows a fourth-generation rancher tasked with bringing order to Las Vegas in the 1960s, when the city was emerging a gambling and entertainment mecca.

Ralph Lamb just wants to run his ranch in peace, but Las Vegas is a fast-growing city, swelling with outsiders and corruption which intrude on his simple life. When the mayor comes to Lamb for help, recalling his command as a military police officer during World War II, Lamb takes the job of Sheriff and clashes with Vincent Savino, a ruthless big city gangster with his own agenda for Las Vegas.

Now these two powerful men engage in a ferocious battle for control of the budding desert oasis.