Frank is an opinionated animal control officer who used to be a cop but got fired for trying to expose corruption in his department. He has a near superhuman ability to understand animals. But humans - that's another story.

Frank is assigned a new partner, Fred "Shred" Taylor, an optimistic rookie. They both report to their sweet-natured and awkward boss Emily. Also in the precinct are Amit and Victoria, partners who could not be more opposite. Rounding out the precinct is veterinarian Dr. Summers, receptionist Dolores, and Templeton, an animal control officer from a neighboring precinct with a real chip on his shoulder.