New student Grace has just arrived at Wallace University, eager to join the Kappa House Sorority, which is led by its queen 'B', Chanel. When anti-Kappa Dean Munsch rules that sorority pledging must be open to all students, rather than just the school's elite, all hell breaks loose.

What appears to start as a normal night takes a terrifying turn. After an "accident" occurs during a pledge initiation, the girls find themselves under attack by a mysterious killer who wreaks havoc by taking them down one by one.