A group of competitive young heroes attending the Godolkin University School of Crimefighting are the first generation to know about Compound V, and that their powers come from an injection rather than being God-given.

These superheroes put their physical and moral boundaries to the test as they vie for the school's highly-coveted top ranking. But when the university's dark secrets come to light, they'll learn that the difference between right and wrong isn't always clear, forcing them to come to terms with the type of heroes want to become.